5-Amino-1MQ research: overview and resources
What 5-Amino-1MQ research material is, how it is characterized, and where to find every specification, method, lot record and reference 5-Amino-1MQ Labs publishes about it.
What is 5-Amino-1MQ?
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small aromatic cation: a quinoline ring system methylated on its ring nitrogen, which gives it a permanent positive charge, with an amino group at position 5. It is not a peptide. It is studied in laboratory research as an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosylmethionine to nicotinamide; its quinolinium core resembles the enzyme's methylated product.
5-Amino-1MQ Labs supplies it as a lyophilized powder in 50 mg vials. Each lot is tested by ILS Laboratories for HPLC purity, identity by retention-time comparison with a reference standard and net content, with a fentanyl screen, and the certificate is published here before sale through Klow.bio.
Because the molecule is a cation, it is always supplied as a salt with a counterion, commonly iodide (C10H11IN2, 286.11 g/mol). The certificate does not state the counterion, so the formula and weight shown here are for the cation itself.
What is 5-Amino-1MQ research material?
5-Amino-1MQ research material is 5-Amino-1MQ supplied for laboratory research (C10H11N2, 159.21 g/mol) in lyophilized powder form, sold by lot. Each lot's identity, purity and net content are documented by an independent laboratory in a published certificate of analysis.
How is 5-Amino-1MQ characterized?
Three questions are answered for every lot, each by a different method:
- Is it the right compound? The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time.
- How much of the sample is that compound? HPLC-UV reports the main peak's share of detected peak area. Current lots: 99.86%.
- How much peptide is in the vial? Net content is measured directly.
Endotoxin (LAL) and microbial DNA (PCR) results are added where those tests are run.
What has not been established
A certificate of analysis describes the specific sample tested on its test date. It does not establish stability afterward, sequence order beyond what mass confirmation shows, results for other lots, or suitability for any particular purpose.
5-Amino-1MQ at a glance
- Product
- 5-Amino-1MQ
- Type
- Small-molecule quinolinium compound
- Also known as
- 5-amino-1-methylquinolinium, 5-amino-1MQ
- Molecular formula (5-amino-1-methylquinolinium cation)
- C10H11N2
- Molecular weight (5-amino-1-methylquinolinium cation)
- 159.21 g/mol (average)
- Form
- Lyophilized powder
- Vial sizes
- 50 mg
- Purity, current lots
- 99.86% (HPLC-UV)
- Purity specification
- ≥95%
- Identity
- Confirmed by HPLC retention-time match on every lot
- Testing laboratory
- ILS Laboratories (independent)
- Current lot
- KB-09573, reported Oct 6, 2026
- Operated by
- Klow Labs LLC, Chicago, IL
- Where to order
- klow.bio
5-Amino-1MQ research resources
Every 5-Amino-1MQ resource on 5amino.bio, organized from chemistry to documentation.
5-Amino-1MQ specifications
Formula, molecular weight, sequence, modifications and release specification.
QualityQuality and supply chain
Sourcing, specifications, batch documentation and release.
TestingAnalytical testing
How every lot is tested, reviewed and released.
TestingHPLC analysis of 5-Amino-1MQ
Retention time, peaks, area normalization and results by lot.
DocumentationCertificates of analysis
Every lot's full results, plus the complete testing records.
DocumentationHow to read a 5-Amino-1MQ COA
What each section means and what a COA does and doesn't establish.
DocumentationVerify a lot
Look up any 5-Amino-1MQ lot by the number on the vial.
AnalysisPurity, content and net content
Three different numbers, kept apart.
HandlingStorage and stability
Degradation pathways and lyophilized peptide handling.
ReferenceGlossary
Definitions for every term on a 5-Amino-1MQ certificate.
Research material5-Amino-1MQ research material
Sizes, current lots and availability. Purchasing is handled through Klow.bio.
Research references
Published sources
- NCBI Gene: NNMT (nicotinamide N-methyltransferase). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/4837
- Wilm M. Principles of electrospray ionization. Mol Cell Proteomics. 2011. PMC3134074. pmc.ncbi.nlm.nih.gov/articles/PMC3134074
- U.S. FDA. Q2(R2) Validation of Analytical Procedures. 2024. fda.gov
- U.S. FDA. Pyrogen and Endotoxins Testing: Questions and Answers. Revised 2026. fda.gov
5-Amino-1MQ Labs analytical documentation
- Lot KB-09573: 50 mg, 99.86% purity, reported Oct 6, 2026
- 5-Amino-1MQ testing records (all tests, all lots; CSV available)
Editorial scope
5-Amino-1MQ Labs research content covers molecular characteristics, peptide structure, analytical chemistry, purity and identity testing, certificates of analysis, lot documentation and laboratory storage and handling.
It does not cover dosing, administration instructions, protocols, personal use or medical advice.
Latest updates
Buy 5-Amino-1MQ
50 mg vials. Current lot KB-09573 tested at 99.86% purity with identity confirmed by HPLC retention-time match against a reference standard. Current purchasing is available through Klow.bio.