What 5-Amino-1MQ is
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small aromatic cation: a quinoline ring system methylated on its ring nitrogen, which gives it a permanent positive charge, with an amino group at position 5. It is not a peptide. It is studied in laboratory research as an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosylmethionine to nicotinamide; its quinolinium core resembles the enzyme's methylated product.
5-Amino-1MQ Labs supplies it as a lyophilized powder in 50 mg vials. Each lot is tested by ILS Laboratories for HPLC purity, identity by retention-time comparison with a reference standard and net content, with a fentanyl screen, and the certificate is published here before sale through Klow.bio.
Because the molecule is a cation, it is always supplied as a salt with a counterion, commonly iodide (C10H11IN2, 286.11 g/mol). The certificate does not state the counterion, so the formula and weight shown here are for the cation itself.
Structure
The quinolinium ring is planar and strongly UV-absorbing, which suits HPLC-UV purity analysis. The positive charge is fixed on the ring nitrogen and does not depend on pH; the 5-amino group is a weak base.
complete 5-Amino-1MQ specifications.
Storage and handling
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. Lyophilized material absorbs moisture from the air, and absorbed moisture restarts the reactions that drying slows, so keep vials sealed until needed. Storage and stability guide.